Development of Protease Inhibitors
Matrix metalloproteinase 9 (MMP-9) is a key enzyme involved in tissue remodeling, inflammation, and pathological conditions such as cancer and vascular diseases. My research has focused on the development of MMP-9 inhibitors as potential therapeutic agents to regulate excessive proteolytic activity. At the Institut de Recherche pour le Développement (IRD) in France, I contributed to identifying and characterizing small molecule and peptide-based inhibitors targeting MMP-9. By utilizing biochemical assays and cellular models, our work aimed to assess their efficacy in restoring endothelial barrier function and mitigating inflammatory responses. These inhibitors hold promise for applications in vascular leakage disorders, fibrosis, and oncology.
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John Doe
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